Why might someone who has never been exposed to TB have a positive PPD?īCG vaccine(Common in those from countries where TB is endemic) Lesions heal/fibrose ⇒ Latent(People usually contract primary TB in childhood) What is the most common outcome of primary TB? Inhibits fusion of phagolysosome ⇒ Allows intracellular survivalĪfter PRIMARY tuberculosis, the following are present:(1) Fibrotic/calcified lung lesions(2) Big hilar lymph nodes(⇒ Fibrosis and calcification = Ranke complex) Stimulates MΦs to make granulomas(It activates MΦs, promoting granuloma formation by stimulating TNF-α release) What culture medium can be used to grow M. What component of the mycobacterial cell wall takes up the Carbol-Fuschin stain? (1) Acid fast(2) Obligate aerobe(Facultative intracellular vs. #SketchyMicro #SketchyMicro::Bacteria::(08)-Mycobacteria::8.2-Mycobacterium_leprae $$Bacteria $MycobacteriaĬharacterize (2) : Mycobacterium tuberculosis (1) Dapsone(2) Rifampin(3) Clofazimine(For up to 5 years) (1) Symmetric glove and stocking neuropathy(2) Skin lesions on extensor surfaces(3) "Leonine facies" Name 3 signs/symptoms of lepromatous leprosy Lepromatous(Notice that they're holding hands, representing transmission) Which form of leprosy has human to human transmission? Inject leprosy antigen ⇒ Type IV hypersensitivity Well demarcated hair loss(Anywhere, not just head) What is the main symptom of tuberculoid leprosy? Th2(⇒ Humoral response ∴ Poorly forms granulomas) Which immune response predominates in the lepromatous form of leprosy?
Which immune response predominates in the tuberculoid form of leprosy? Why does Leprosy predominantly affect the extensor surfaces?
#SketchyMicro #SketchyMicro::Bacteria::(05)-Gram_(-)_Bacilli-GI::5.03-Shigella $$Bacteria $Gram_(-)_Bacilli-Enteric Name 3 enteric bacteria with Type III secretion systems Also associated with Reitter's syndrome.) What type of diarrhea does Shigella cause?Ĭhildren <10 years old(Due to Shigella DYSENTERIAE. (1) Induces phagocytosis by M-cells(2) Uses actin filaments to escape(Once escaped, it's phagocytosed by MΦs, and then induces apoptosis and subsequent Inflammation.) ShigellaSalmonellaGreen on HektoenBlack on HektoenImmotileMotileAcid stableAcid labile
Name 3 ways you can distinguish Shigella from Salmonella The front and back of a card, you can do so by clicking the Edit When this deck is imported into the desktop program, cards will appear
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